Evaluation of the Possible Transmission of BSE and Scrapie to Gilthead Sea Bream (Sparus aurata) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0006175 FULL TEXT ; http://madcowfeed.blogspot.com/2009/06/farmed-fish-may-pose-risk-for-mad-cow.html Monday, July 27, 2009 U.S.A. HIDING MAD COW DISEASE VICTIMS AS SPORADIC CJD ? http://creutzfeldt-jakob-disease.blogspot.com/2009/07/usa-hiding-mad-cow-disease-victims-as.html TSS

I believe Dr. Friedland is guilty of the alarmist hype endemic to prion research. The ‘mad-cow epidemic' has so far resulted in less than 200 fatalities – hardly a prescient threat to human health. First, fish prion protein (or prion-like proteins) share little homology with their mammalian counterparts and would be exceedingly unlikely to amplify the infectious mammalian prion conformation either in vitro or in vivo (i.e. fish cannot contract mad cow). Second, while feeding of bovine-derived meat and bone meal to livestock such as chickens may contribute to the spread of BSE, this is due to the subsequent use of chicken droppings as filler in cattle feed. Are fish droppings utilized in a similar manner? Third, in studies where fish are infected with mammalian prions, the fish are force fed infected mouse brain homogenate. Even with this massive overload of infectious prions, their immunodetection indicates that they are essentially cleared from the fish digestive system within 24 hours, and subsequent injection of these intestines (at 1 day post challenge) directly into mouse brain reveals negligible infectivity, indicating a VERY low, if any, infectivity titre. After researching the conformational conversion of the prion protein for four years I am convinced that, while an interesting biological phenomenon, the human dangers associated with prion disorders have been vastly overstated to a confused and uninformed public. Medical hypotheses such as that presented here in this article can only i) divert funding away from more important human health concerns and ii) alarm scientifically illiterate legislators to the point where unnecessary regulation is written, passing the cost associated onto the consumer. While there remains an infinitesimal chance that BSE could spread in the manner described by Dr. Friedman (given that no one has proven it cannot occur), I suggest we all relax and belly up for some surf and turf.

I strongly believe that mad cow disease and Alzheimer are often one and the same. I think an epidemic is just around the corner. A simple solution and before it is too late one should become vegan.

PLEASE REMEMBER, even if fish could not contract a Transmissible Spongiform Encephalopathy, it would still be possible for the TSE agent to survive the digestinal tract, and then if that fish was added as an ingredient for feed, the agent could further spread to infect other species. ...TSS PRODUCT a) Tucker Milling, LLC Tm 32% Sinking Fish Grower, #2680-Pellet, 50 lb. bags, Recall # V-121-6; Tucker Milling, LLC #31120, REASON Poultry and fish feeds which were possibly contaminated with ruminant based protein were not labeled as "Do not feed to ruminants". DISTRIBUTION AL, GA, MS, and TN END OF ENFORCEMENT REPORT FOR AUGUST 9, 2006 ### http://www.fda.gov/bbs/topics/ENFORCE/2006/ENF00964.html http://madcowfeed.blogspot.com/2009/03/millions-and-millions-of-pounds-of-mad.html Wednesday, April 02, 2008 In vivo prion protein intestinal uptake in fish 1: APMIS. 2008 Mar;116(3):173-80. In vivo prion protein intestinal uptake in fish. Results indicate that PrP(Sc) was absorbed by the intestinal mucosa and that it persisted in the fish gastrointestinal tract for up to 3 days in pyloric caeca and for up to 7 days in the distal intestine. It did not remain longer than 15 days in the fish intestine; WOULD this not be a potential risk factor for transmission of the PrPSc agent to cattle and other species via fish by-products and or fish feed ??? http://madcowspontaneousnot.blogspot.com/ http://bse-atypical.blogspot.com/2009/06/l-type-bse-h-type-bse-c-type-bse-ibnc.html http://cjdusa.blogspot.com/2009/06/monitoring-occurrence-of-emerging-forms.html Sunday, June 7, 2009 ALZHEIMER'S DISEASE IS TRANSMISSIBLE http://betaamyloidcjd.blogspot.com/2009/06/alzheimers-disease-is-transmissible.html Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518

Greetings Jessica, please pass this on to Dr. Friedland....... PLEASE REMEMBER, even if fish could not contract a Transmissible Spongiform Encephalopathy, it would still be possible for the TSE agent to survive the digestinal tract, and then if that fish was added as an ingredient for feed, the agent could further spread to infect other species. ...TSS PRODUCT a) Tucker Milling, LLC Tm 32% Sinking Fish Grower, #2680-Pellet, 50 lb. bags, Recall # V-121-6; Tucker Milling, LLC #31120, Game Bird Breeder Pellet, 50 lb. bags, Recall # V-122-6; c) Tucker Milling, LLC #31232 Game Bird Grower, 50 lb. bags, Recall # V-123-6; d) Tucker Milling, LLC 31227-Crumble, Game Bird Starter, BMD Medicated, 50 lb bags, Recall # V-124-6; e) Tucker Milling, LLC #31120, Game Bird Breeder, 50 lb bags, Recall # V-125-6; f) Tucker Milling, LLC #30230, 30 % Turkey Starter, 50 lb bags, Recall # V-126-6; g) Tucker Milling, LLC #30116, TM Broiler Finisher, 50 lb bags, Recall # V-127-6 CODE All products manufactured from 02/01/2005 until 06/20/2006 RECALLING FIRM/MANUFACTURER Recalling Firm: Tucker Milling LLC, Guntersville, AL, by telephone and visit on June 20, 2006, and by letter on June 23, 2006. Manufacturer: H. J. Baker and Brothers Inc., Stamford, CT. Firm initiated recall is ongoing. REASON Poultry and fish feeds which were possibly contaminated with ruminant based protein were not labeled as "Do not feed to ruminants". VOLUME OF PRODUCT IN COMMERCE 7,541-50 lb bags DISTRIBUTION AL, GA, MS, and TN END OF ENFORCEMENT REPORT FOR AUGUST 9, 2006 ### http://www.fda.gov/bbs/topics/ENFORCE/2006/ENF00964.html In vivo prion protein intestinal uptake in fish. http://www.ncbi.nlm.nih.gov/pubmed/18377582?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum http://bse-atypical.blogspot.com/2009/06/l-type-bse-h-type-bse-c-type-bse-ibnc.html

So these fish are eating rendered cow products from cows that were not fed rendered cow products but I'm supposed to be concerned about Mad Cow Disease still? So if my boy tells me a lie or says something I don't like and wash his mouth out with soap, am I to be worried I might be inflicting him with this horrible disease? Sounds a little fishy to me.